به نام خداوند بخشاینده مهربان
   [Home ] [Archive]   [ فارسی ]  
:: About :: Current Issue :: Archive :: Search :: Submit :: Contact ::
:: Volume 5, Issue 3 (Autumn 2019) ::
Health_Based Research 2019, 5(3): 261-272 Back to browse issues page
Comparison of the Therapeutic Effects of Topiramate and Phenobarbital on the Quality of Life of Children under Five with Fever and Convulsion
Hamid Talebianpour , Elham Talebianpour , Hamid Nemati , Khosro Keshavarz
Abstract:   (275 Views)
Comparison of the Therapeutic Effects of Topiramate and Phenobarbital on the Quality of Life of Children under Five with Fever and Convulsion
 
Talebianpour Hamid 1, Talebianpour Elham 2, Nemati Hamid 3, Keshavarz Khosro 4*

1. PhD Student in Health Economics, Student Research Committee, Tehran University of Medical Sciences, Tehran, Iran
2. MSc Student in Nursing, Student Research Committee, Yasuj University of Medical Sciences, Yasuj, Iran
3. Assistant Professor of Pharmacoeconomics and Pharmaceutical Administration, Health Human Resources Research Center, School of Management & Medical Informatics, Shiraz University of Medical Sciences, Shiraz, Iran
4. Assistant Professor of Pediatric Neurology, Neuroscience Research Center, Shiraz University of Medical Sciences, Shiraz, Iran
* Corresponding Author: Khosro Keshavarz
Address: Alley 29, Qasr al-Dasht Street Molla Sadra Intersection, Shiraz
Tel: 00987132340774                                               Email: khkeshavarz2007@gmail.com
Abstract:
Background & Objectives: Failure to treat febrile seizure in children leads to physical, psychological and social problems and if not treated timely, might lead to epilepsy which affects the quality of life of children. The purpose of this study was to compare the therapeutic effects of two drugs on the quality of life of children under five with febrile convulsion.
Methods: This was a descriptive-analytical study that was done in an interventional manner. In this study, the quality of life of 40 children with febrile convulsion treated with topiramate and 51 children who had the same problem and treated with phenobarbital drug were compared. Data collection tool was EQ5D questionnaire. ANOVA and t-test were used for statistical analysis and data were entered into SPSS statistical software version 22.
Results: Mean scores of quality of life in children taking phenobarbital and topiramate were 72.5 and 82.7, respectively. Topiramate had a significant effect on the mean score of quality of life in children with febrile convulsion and increased it. Parental education and early febrile convulsion had a significant relationship with patients' quality of life. 
Conclusion: Health policy makers, physicians, and other members of health care system must provide access to appropriate educational, medical, and therapeutic services for children with febrile seizure in order to improve their health status.
 
Key­words: Febrile convulsion, Topiramate, Phenobarbital, Quality of Life, Children
 
Citation: Talebianpour H, Talebianpour E, Nemati H, Keshavarz K. Comparison of the Therapeutic Effects of Topiramate and Phenobarbital on the Quality of Life of Children under Five with Fever and Convulsion. Journal of Health Based Research 2019; 5(3): 261-72.
Keywords: Febrile convulsion, Topiramate, Phenobarbital, Quality of Life, Children
Full-Text [PDF 1468 kb]   (40 Downloads)    
Type of Study: Research |
Send email to the article author

Add your comments about this article
Your username or Email:

CAPTCHA


XML   Persian Abstract   Print


Download citation:
BibTeX | RIS | EndNote | Medlars | ProCite | Reference Manager | RefWorks
Send citation to:

Talebianpour H, Talebianpour E, Nemati H, Keshavarz K. Comparison of the Therapeutic Effects of Topiramate and Phenobarbital on the Quality of Life of Children under Five with Fever and Convulsion. Health_Based Research. 2019; 5 (3) :261-272
URL: http://hbrj.kmu.ac.ir/article-1-317-en.html


Volume 5, Issue 3 (Autumn 2019) Back to browse issues page
نشریه پژوهش های سلامت محور Journal of Health Based Research
Persian site map - English site map - Created in 0.06 seconds with 32 queries by YEKTAWEB 4106